Reduced biocide susceptibility in Candida albicans biofilms.

نویسندگان

  • Jeniel E Nett
  • Kristie M Guite
  • Alex Ringeisen
  • Kathleen A Holoyda
  • David R Andes
چکیده

Candida biofilm formation is common during infection and environmental growth. We tested the impacts of three biocides (ethanol [EtOH], H(2)O(2), and sodium dodecyl sulfate) on Candida albicans, C. parapsilosis, and C. glabrata biofilms. Higher concentrations of the biocides were required for efficacy against biofilms than for efficacy against planktonic controls. A combination study with two biocides (EtOH and H(2)O(2)) and fluconazole demonstrated that the combination had enhanced efficacy.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 52 9  شماره 

صفحات  -

تاریخ انتشار 2008